If you love cheesy, creamy, and crunchy dishes packed with bold Tex-Mex flavors, then this Mexican White Trash Casserole is about to become your new favorite meal! This easy-to-make, ultra-comforting casserole layers crushed nacho-flavored Doritos with seasoned chicken or ground beef, a rich and creamy sauce, and plenty of melted cheese. It’s perfect for busy weeknights, potlucks, or whenever you need a dish that’s guaranteed to please a crowd.

This quick-prep casserole is made with pantry-friendly ingredients and requires minimal effort, making it an excellent go-to dinner option. Whether you serve it with a fresh side salad, rice, or enjoy it on its own, every bite is a satisfying combination of creamy, cheesy, and crunchy textures.

Why You’ll Love This Recipe

Quick & Easy – Simple ingredients and minimal prep time.

Family-Friendly – A dish that both kids and adults will love.
Comforting & Hearty – A filling meal that satisfies with every bite.
Perfect for Potlucks – Easy to make in a large batch and always a crowd-pleaser.

Customizable – Adapt it with different proteins, toppings, or spice levels.

If you enjoy Doritos taco casserole, cheesy Mexican dishes, or classic comfort food, this dish will be a hit at your table!

Ingredients You’ll Need

To create this irresistible casserole, gather the following ingredients:

1 bag Nacho Doritos, crushed – Adds a crispy, flavorful base and topping.
2 cups shredded chicken or ground beef – Choose your preferred protein for a heartier dish.
2 cups shredded cheese – A mix of cheddar and Monterey Jack works great.

1 can (10.75 oz) cream of chicken soup – Provides a creamy, rich texture.
1 can Rotel tomatoes, undrained – Brings in a bit of spice and tomato flavor.
1/2 cup sour cream – Enhances the creaminess and balances the flavors.

1/2 cup milk – Helps create a smooth consistency in the sauce.
1/2 package taco seasoning (or more, to taste) – Gives the dish a classic Mexican-inspired kick.

Each ingredient plays a role in building the perfect balance of crunch, creaminess, and bold Tex-Mex flavor.

Step-by-Step Instructions

Step 1: Preheat Your Oven

Preheat your oven to 350°F (175°C). Lightly grease a 2-quart casserole dish with nonstick cooking spray.

Step 2: Prepare the Filling

In a large mixing bowl, combine:

Shredded chicken or cooked ground beef

Shredded cheese (reserve some for topping)
Cream of chicken soup
Rotel tomatoes

Sour cream
Milk
Taco seasoning

Stir everything together until well combined.

Step 3: Assemble the Casserole

Layer Half of the Crushed Doritos – Spread evenly at the bottom of the greased casserole dish.
Add Half of the Meat Mixture – Spread evenly over the Doritos layer.

Repeat with Another Layer of Doritos followed by the remaining meat mixture.
Top with Extra Cheese – Sprinkle the reserved shredded cheese on top for a melty, cheesy finish.

Step 4: Bake Until Bubbly

Cover the casserole dish with aluminum foil to keep moisture in.

Bake for 35 minutes (increase to 45 minutes if doubling the recipe).
Remove the foil and bake for another 5-10 minutes to achieve a slightly crispy cheese topping.

Step 5: Serve and Enjoy!

Let the casserole rest for a few minutes before serving. This helps the layers set and makes serving easier. Serve warm with optional garnishes like chopped cilantro, diced avocado, or a dollop of sour cream.

Delicious Variations & Add-Ins

Want to switch things up? Try these fun twists:

Make It Spicier – Use spicy taco seasoning, add diced jalapeños, or mix in hot sauce.

Swap the Protein – Use shredded rotisserie chicken, ground turkey, or black beans for a different taste.
Add More Crunch – Sprinkle crushed tortilla chips or Fritos on top for extra texture.
Make It Creamier – Stir in extra sour cream or cream cheese for a richer texture.

Add Veggies – Toss in corn, black beans, or diced bell peppers for extra nutrition.
Low-Carb Version – Replace Doritos with crushed pork rinds or use cauliflower rice instead of chips.

This recipe is highly adaptable, making it easy to adjust based on personal preferences or dietary needs!

Expert Tips for the Best Casserole

Use Freshly Shredded Cheese – Pre-shredded cheese contains anti-caking agents that affect melting.
Don’t Overbake – Baking too long can dry out the casserole; keep an eye on it.
Let It Rest – Allowing the casserole to sit for a few minutes helps set the layers.

Prep Ahead – Assemble the casserole up to 24 hours in advance and bake when ready.
Store Leftovers Properly – Keep in an airtight container in the refrigerator for 3-4 days.

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes! Assemble the casserole and store it covered in the refrigerator for up to 24 hours. When ready, bake as directed.

How do I store and reheat leftovers?

Store leftovers in an airtight container in the refrigerator for up to 3-4 days. Reheat in the oven at 350°F for 10-15 minutes or in the microwave until warm.

Can I freeze this casserole?

Yes! Prepare and assemble the casserole, but don’t bake it yet. Cover tightly and freeze for up to 3 months. Thaw overnight in the fridge before baking.

What can I serve with this dish?

Pair it with a side salad, guacamole, salsa, black beans, or Spanish rice for a complete meal!

Is this recipe gluten-free?

No, but you can easily make it gluten-free by using gluten-free taco seasoning and gluten-free chips.

Final Thoughts

Mexican White Trash Casserole is the ultimate easy-to-make, comfort food that never fails to impress. With its bold flavors, cheesy layers, and crunchy Doritos topping, it’s a dish the whole family will love. Whether you’re making it for a weeknight dinner, a potluck, or a game day feast, this creamy, cheesy, and crunchy casserole will always be a winner.

Mexican White Trash Casserole

Author: Diana Carrozza

Print Recipe

Description

This bold and cheesy Mexican White Trash Casserole is the ultimate comfort food! Made with layers of crunchy Nacho Doritos, seasoned chicken or beef, melty cheese, and a creamy, zesty filling, this dish is packed with flavor. Baked to perfection, it’s an easy, crowd-pleasing meal perfect for busy weeknights or potlucks. Serve warm and enjoy the irresistible mix of textures and flavors!

Ingredients

Scale

1 bag Nacho Doritos, crushed
2 cups shredded chicken or ground beef
2 cups shredded cheese (more if desired)
1 can (10.75 oz) cream of chicken soup
1 can Rotel tomatoes, undrained
1/2 cup sour cream
1/2 cup milk
1/2 package taco seasoning (or more, to taste)

Instructions

Preheat your oven to 350°F (175°C). Prepare a 2-quart casserole dish by spraying it with nonstick cooking spray. This helps prevent sticking and ensures easy cleanup.
In a large mixing bowl, combine the shredded chicken or ground beef, shredded cheese, cream of chicken soup, Rotel tomatoes, sour cream, milk, and taco seasoning. Mix well to ensure all ingredients are thoroughly combined. This mixture is the creamy, flavorful base of your casserole.
Start by spreading half of the crushed Doritos evenly at the bottom of the prepared casserole dish. This will form a crunchy base.
Next, layer half of the chicken or beef mixture over the Doritos. Spread evenly to cover the Doritos layer.
Repeat with another layer of crushed Doritos followed by the remaining chicken or beef mixture.
Optionally, top with an additional layer of shredded cheese, which will create a delicious, melty top layer.
Cover the casserole dish with aluminum foil. This helps to keep the moisture in and prevents the top from burning.
Place in the preheated oven and bake for 35 minutes. If you are doubling the recipe and using a larger 9×13 inch pan, increase the baking time to 45 minutes. This ensures everything is thoroughly heated through and the cheese becomes bubbly.
Remove the casserole from the oven and let it sit for a few minutes before serving. Allowing it to rest helps the layers set slightly, making it easier to serve neatly.
Serve warm. This dish is perfect as a hearty main course and is sure to be a hit with those who enjoy a good, comforting meal with a touch of Mexican

Notes

Meat Choices: Use shredded chicken for a milder taste or ground beef for a heartier version.
Doritos Swap: Try Cool Ranch or Spicy Nacho Doritos for a different flavor twist.
Make It Spicy: Add diced jalapeños, extra taco seasoning, or hot sauce for a kick.

Cheese Lovers: Add extra cheese on top for an extra gooey, cheesy finish.
Storage: Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the oven for best results.

Mexican White Trash Casserole: A Cheesy, Crunchy, and Irresistible Comfort Food